The Technical Department at DuPont's Carney's Point Works was established to collaborate with scientists at the DuPont Experimental Station and Eastern Laboratory of the Repauno Works to develop new products, maintain quality control, and improve products and processes. The collection focuses on the department's start-up period (1906-1910) and the two World Wars.

Frederick J. LeMaistre (1879-1944) was a chemical engineer employed by the E.I. du Pont de Nemours Powder Company at its Eastern Laboratory for fourteen years. This collection consists of ten volumes; seven are LeMaistre's laboratory notebooks documenting his work on nitrates, nitroglycerin, artificial silk (rayon), pyralin, and solvents. Also included are two souvenir logbooks of tours by the American Institute of Chemical Engineers and one Niagara Oil Company of Philadelphia cashbook.

During his lifetime, French botanist Michel Adanson (1727-1806) assembled a large number of notes and documents for a projected but never completed scientific encylcopedia. This collection of Adanson's notes focuses on nitrates, including saltpeter.