The Centennial Exhibition of 1876 celebrated the one-hundredth anniversary of American Independence. Held in Fairmount Park in Philadelphia, it was the first major U.S. world's fair. The collection consists of color-printed cards with views of the exhibition. Included are five views of the major buildings, thirteen state buildings (including Delaware), three international buildings, and one fountain.

David Jayne (1798-1866) purchased a drug store in Philadelphia in 1836. His patent medicine business grew quickly and he built this new building in 1850. The building was designed by American architects, William J. Johnston (1811-1849) and Thomas U. Walter (1804-1887) and was located at 242 Chestnut Street in Philadelphia, Pennsylvania. The firm of Dr. D. Jayne and Son was one of the largest patent medicine firms in the United States, and this building was "the most conspicuous building of the time" in Philadelphia. Engraved on wood and printed by William B. Gihon (dates unknown), an illustrator and engraver.