The DuPont Company's Chestnut Run Laboratories were opened in 1954 near Wilmington, Delaware. The first laboratory was the Textile Research Laboratory whose purpose was to test the effects of normal wear and tear on DuPont's line of synthetic fibers and fabrics. This collection consists of eight albums of photographs showing laboratories, fabrication equipment, testing equipment dating to the mid-1950s, and personnel photographs from the late-1980s.

Donald Robert Hull (1911-1995) was a longtime employee at the DuPont Company mainly working with nylon and textile fibers. The collection consists of four scrapbook albums of material from Donald Hull's career with the Du Pont Company.

The Textile Fibers Department of the DuPont Company, established in 1936 as the Rayon Department, specialized in researching and developing synthetic fibers for fabrics such as Rayon, Nylon, Teflon, Corian, and Kevlar. This collection primarily contains video tapes (VHS and U-Matic). Most of the content on the VHS videotapes are different than that on the U-Matic videotapes, there are a few duplicate videos that are in both formats. The videotapes content are employee training videos related to management, customer service and safety, as well as, informational videos about product and services, company history and events. Additionally the collection contains photographs, slides, advertising and promotional materials.

E.I. du Pont de Nemours & Company is a chemical company more commonly referred to as the DuPont company, established in 1802. DuPont's Chestnut Run Laboratories was opened in 1954 near Wilmington, Delaware. This collection consists of two albums documenting the history of the Chestnut Run facility between 1954 and 1961. One album contains primarily photographs taken of the facilities exteriors between 1955 and 1958. The second album contains mostly newspaper clippings between 1954 and 1961.