Victor Marie du Pont (1767-1827) was a French diplomat. In 1794, he married Gabrielle Joséphine de La Fite de Pelleport (1770-1837), and a year later they came to the United States, where he was appointed as consul at Charleston, South Carolina. They returned to France in 1798, but came back to the United States in 1800 with their children; his father, Pierre Samuel du Pont de Nemours (1739-1817); and his younger brother, Éleuthère Irénée du Pont (1771-1834), and his family. Victor and Josephine du Pont had five children, four surviving to adulthood: Amelia Elizabeth (1796-1869), Charles Irénée (1797-1869), Samuel Francis (1803-1865), and Julia Sophie (1806-1882). (The papers of Samuel Francis Du Pont, husband of Sophie Madeleine Du Pont, are held in Group IX of the Winterthur Manuscripts.)

Amelia du Pont was the eldest child of Victor du Pont and Gabrielle Joséphine (de La Fite de Pelleport) du Pont. Her 1812 marriage to William H. Clifford was annulled by an act of the General Assembly of Delaware. She was the godchild of the Chevalier de Ternant, French minister to the U.S., who gave her substantial lands in Pennsylvania. She spent most of her life in Delaware but moved to Scranton, Pennsylvania, in 1860 to live with her daughter, Gabrielle Josephine (du Pont) Breck (1813-1891).

Charles Irénée du Pont was born on March 29, 1797. He studied at Mt. Airy College in Germantown, Pennsylvania, from 1809 to 1813, when he left school to enter business with his father. Upon the dissolution of the firm of Du Pont, Bauduy & Co., they formed the partnership of Victor & Charles I. du Pont de Nemours & Co. in 1815, for the operation of a woolen factory at Louviers, a site located across the Brandywine River from the powder factory of E. I. du Pont de Nemours & Co. After the death of his father in 1827, the firm continued to operate as Charles I. du Pont & Co. until 1856, when Charles I. du Pont retired and the interests of the company were acquired by E. I. du Pont de Nemours & Co. An important part of the woolen business had been in supplying cloth to the United States for Army use.

Charles I. du Pont married Dorcas Montgomery Van Dyke (1806-1838) in 1824. In 1841, he married Ann Ridgely (1815-1898). Du Pont was active in civic and political affairs. In 1817, he became a trustee of the Brandywine Manufacturers' Sunday School. In 1830, he was elected a director of the Farmers Bank of the State of Delaware, at Wilmington, and continued as such for many years; he was president of the bank from 1865 to 1868. In 1833, he was an incorporator of the New Castle Manufacturing Co., established for the manufacture of cotton, woolen, and metal goods. He served two terms in the Delaware Senate, from 1841 to 1845 and from 1853 to 1857. In 1853, he was an incorporator and director of the Delaware Railroad Co. He was also a director of the Columbia Insurance Co. of Philadelphia, and of the Philadelphia, Wilmington & Baltimore Railroad Co., as well as a vice president of the Delaware Improvement Association. Du Pont resided at Louviers, the home built by his father, and died there on January 31, 1869.

Dorcas Montgomery Van Dyke (1806-1838) was the daughter of Nicholas Van Dyke (1769-1826) and Mary Van Lekvenigh Van Dyke (1768-1831) of New Castle, Delaware. The Van Dyke male family members were active in government, with Nicholas Van Dyke serving in both the state and federal government. He was a member of the U.S. Senate from 1817 to 1826. Dorcas Van Dyke married Charles I. du Pont in 1824. The Marquis de Lafayette attended the wedding. The couple had five children. She died in 1838 after a long illness.

Ann Ridgely (1815-1898), the daughter of Henry Moore Ridgely (1779-1847) and Sarah Banning Ridgely (1787-1837) of Delaware, married Charles I. du Pont in 1841, and was his second wife. They had two children.

Julia Sophie Angélique du Pont became the wife of Irvine Shubrick (1797-1849) in 1824. He was one of the four sons of Colonel Thomas Shubrick (1755-1810) and Mary Branford Shubrick (1757-1832), of South Carolina, all of whom had notable careers in the United States Navy. Shubrick entered the Navy in 1814 and served under Stephen Decatur in the Algerine War. He was commissioned a lieutenant in 1825. From 1831 to 1834 he served in the Pacific. After taking command of the Saratoga he was on the Brazil station from 1844 to 1847. His last post was that of inspector at the Philadelphia Navy Yard, from 1848 to his death in 1849.

Of his five children, the eldest, Thomas Branford Shubrick (1825-1847), had a naval career, and was killed in action at Veracruz, while a daughter, Alicia Cecelia Shubrick (1830-1894), entered a convent and was afterward known as Mother Mary Jerome. Another daughter, Gabrielle Josephine Shubrick (1835-1894), married Robert Erskine Anderson Crofton (1834-1898) of the United States Army, who was cited for gallantry in the battles of Shiloh, Chickamauga, and Missionary Ridge during the Civil War, and later served at western outposts.