The Science and Technology Department series is arranged in two subseries: Committees, subcommittees, and task forces, and Subject files. This material should be considered in conjunction with the Resources and Technology Department material.

The Committees, subcommittees, and task forces subseries contains mailings, meeting material, member lists, minutes, and agendas from various committees and subcommittees. The material is arranged by committee or subcommittee and then chronologically. Some of the committees and subcommittees represented include Oceanography Subcommittee, Patents Committees, Research Committee, and Water Resources Research Subcommittee.

The Subject files subseries consists of files that were maintained by the Science and Technology Department on a variety of topics of interest to the department and likely used as reference. Several subjects are included, but main subjects are the FCC on interdependence of computer and communication services and facilities, oceans, patents, and trademarks.