The Plant sites series consists of images of DuPont industrial sites and office buildings, both in the United States and at international locations. The images included in this series feature the location or worksite as the primary subject or focus; this includes factory or office interiors, which depict manufacturing processes and office work. The employees are not the focal point of the images. Often (though not always), the employee is unidentified; in some cases, the employee may even be a model, not an actual employee. The purpose of the image is to highlight the process of the work or the workplace itself.

Plant sites are arranged by the plant's most commonly used plant name, with the location in parenthesis. A few of the DuPont plants have multiple names; in these cases, each name has been supplied. Some plants have multiple laboratories on the same site; for example, both Jackson Laboratory and Chambers Works are located at the Deepwater Point Works and are listed under the letter "D."

The images exist in several different formats: photographic prints, negatives, transparencies, and slides. Sometimes there are negatives or slides for photographic prints or contact sheets; there are often unique images in unique formats. There is an imbalance of coverage. Some plant sites have only a single image, while others have a considerable number of views. Some only have a picture of a sign for the plant or an aerial, while others document numerous buildings and processes.

There are a large number of aerial photographs of plant sites and exterior views, as well as interior views of empty spaces and interiors showing employees working. There is documentation of the manufacturing process for some products. When a specific plant is identified, images of that plant are filed under the plant site name; if there is no plant associated with the images, they have been organized by product name.

Manufacturing images in the Plant sites series show factory machinery and product manufacture as the image subject rather than the finished product itself. For images of the finished product, see the Products series.