Lammot du Pont (1831-1884) was an accomplished chemist who managed gunpowder manufacturing at the E.I. du Pont de Nemours & Co. (commonly called the DuPont Company). He later organized the Repauno Chemical Company to manufacture dynamite. The papers describe his innovative work in the explosives industry, outside investments in coal mines and railroads, and correspondence with family members. There is also a small subset of materials compiled by his son, also named Lammot du Pont (1880-1952), on various du Pont family and company historical topics.

The Natrona Alkali Company was incorporated to hold title to 1,600 acres of sodium carbonate deposits in Natrona County by the descendants of chemist, Lammot du Pont (1831-1884), who developed B blasting powder, using Chilean sodium nitrate and had hoped that the sodium carbonate might become a substitute for imported sodium nitrate in the manufacture of explosives, but the deposits turned out to have no commercial application. The Natrona Alkali Company records are primarily the corporate records related to a second incorporation of the company due to a clerical oversight, the materials date from 1950 to 1980, though there are some documents from the ealier company.

Sophie Madeleine du Pont (1810-1888) was the youngest daughter of Eleuthère Irénée du Pont (1771-1834), founder of E.I. du Pont de Nemours & Co., and Sophie Madeleine Dalmas du Pont (1775-1828), and the wife of Samuel Francis du Pont (1803-1865). The letter from du Pont to Lammot du Pont (1831-1884) concerns the disposal of a book of her husband's on marine artillery.