Alice Lea Spruance (1876-1967) was the daughter of Delaware governor Preston Lea (1841-1916) and his first wife Adelaide Moore (1846-1888). Since the 1770s, the Lea family were among the largest flour mill operators at the Brandywine Falls, north of Wilmington, Delaware. This collection of personal and business papers document Spruance's personal investments, a diversified portfolio of stocks and bonds that was managed by her relative Alfred E. Bissell (1903-1975) of Laird, Bissell & Meeds, brokers. Also included are descriptions, anecdotes, memoranda, and clippings relating to Wilmington and the Brandywine area, particularly the Brandywine Mills, the source of the Lea family's wealth.

William Corbit Spruance (1873-1935) was an electrical engineer and Vice President in Charge of Production at E.I. du Pont de Nemours & Company. His wife, Alice Moore Lea Spruance (1876-1967), was a member of a Wilmington, Delaware, flour-milling dynasty. Spruance family miscellany contains threes letters, two regarding a forestry bill and one a thank you letter. Additionally, there are two copies of a newspaper article titled "This was the Civil War".