Science and Corporate Strategy is a scholarly history of Research and Development at the DuPont Company authored by David A. Hounshell (1950-) and John Kenly Smith (1951-). The collection consists of research files compiled by Hounshell Smith for the purpose of writing the book. Research files include copies of correspondence, articles, reports, patents, chronologies, organizational charts, and contracts from the DuPont Company from 1903 though 1980.

The Central Research and Development Department was the main research arm of E. I. du Pont de Nemours & Co., also known as the DuPont Company. It had its origins in the Development Department, which formed in 1903 and operated at the Experimental Station (the company's main research and development facility) in Wilmington, Delaware. In 1911, the Chemical Department was formed, renamed in 1958 as the Central Research Department. All company research came under its jurisdiction. In 1975, these two departments merged to become the Central Research and Development Department. This collection represents fairly complete documentation of the Central Research and Development Department's research activities, particularly during the 1930s when neoprene and nylon were developed.

James R. Thomen (1926-) was manager of the Experimental Station from 1975 to 1985 when he retired. The DuPont Company's Experimental initially, was to be a small laboratory to screen inventions which were coming into the company from outside independent inventors specifically for research on black powder, smokeless powder, and dynamite, but soon its mission was altered and it became a large industrial research facility focused on innovative advancements in chemistry. This collection consists primarily of photographs of buildings at the Experimental Station in Wilmington, Delaware taken between 1910 and 1950.