Science and Corporate Strategy is a scholarly history of Research and Development at the DuPont Company authored by David A. Hounshell (1950-) and John Kenly Smith (1951-). The collection consists of research files compiled by Hounshell Smith for the purpose of writing the book. Research files include copies of correspondence, articles, reports, patents, chronologies, organizational charts, and contracts from the DuPont Company from 1903 though 1980.

The Central Research and Development Department was the main research arm of E. I. du Pont de Nemours & Co., also known as the DuPont Company. It had its origins in the Development Department, which formed in 1903 and operated at the Experimental Station (the company's main research and development facility) in Wilmington, Delaware. In 1911, the Chemical Department was formed, renamed in 1958 as the Central Research Department. All company research came under its jurisdiction. In 1975, these two departments merged to become the Central Research and Development Department. This collection represents fairly complete documentation of the Central Research and Development Department's research activities, particularly during the 1930s when neoprene and nylon were developed.