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Wallace Hume Carothers (1896-1937) was a chemist and inventor of Neoprene artificial rubber and Nylon synthetic fiber. He worked as a chemist in E.I. du Pont de Nemours & Company's Fundamental Research Program from 1928 until his death in 1937. This small collection consists of Carothers' professional and technical correspondence, primarily with colleagues in the Chemistry Department at Iowa State University, Harvard, and the DuPont Company. The papers describe the DuPont Company's recruitment of Carothers and his work on polymerization, which led to the development of Nylon.