John Raven Johnson (1900-1988) was a professor of chemistry at Cornell University from 1930 until his retirement in 1965. He also served as a consultant to E.I. du Pont de Nemours & Company from 1937 until 1951, where he worked for the Organic Chemicals Department. Wallace Hume Carothers (1896-1937) was a chemist and inventor of Neoprene artificial rubber and Nylon synthetic fiber. He worked as a chemist in E.I. du Pont de Nemours & Company's Fundamental Research Program from 1928 until his death in 1937. This collection consists of correspondence between Johnson and Carothers, who were close friends as well as colleagues. The letters are both professional and personal in nature. Several letters discuss laboratory research work in polymer chemistry and the role of the catalyst.