The collection primarily consists of correspondence, memoranda, and reports documenting Reisner's research in electron microscopy and the RCA VideoDisc. Reisner's personal life and his service to the church and community is also described via personal correspondence and meeting notes.

Photographs and slides document the different types of electron microscopes including Electron Emission Microscope, Reflection Electron Microscope, as well as EM-3 and EM-75 Microscopes. They also document the use of the microscope and how it is impacted by diffraction, optical reconstruction apparatus, contamination as a function of electrical charge density, carbon film thickness impact on transmission, and the impact of temperature on level of contamination. Other images show substances including diseases (polio virus, influenza virus, necrosis virus, and tumors) everyday objects (soap), and chemical elements (lead oxide). There are also images of Trichocysts from Paramecium and Paramyosin Fibril stain with Phosphotungstic Acid.

One of Reisner's lab notebooks (1979-1982) can be found in Record group 26.