This series contains genealogical and biographical information on Sperry and his family. Included is a diary of Stephen Decatur Sperry (Elmer's father), genealogical charts tracing the family roots to England and the reign of Charles I, and letters from Elmer Sperry describing his early life in Cortland and experiences at Cornell University. This series also includes correspondence of Zula Goodman Sperry (Elmer's wife) and her brother. Herbert Goodman. describing the role the Goodman family played in Elmer Sperry's various enterprises.

This series includes Sperry's correspondence with Thomas Edison (a colleague on the Naval Advisory Board) and with Helen Keller. There is also information on Sperry's personal finances and condolences which were written to him after the death of his son, Lawrence.