E.I. du Pont de Nemours & Company was established in 1802 by Pierre Samuel du Pont de Nemours (1739-1817) and his son Éleuthère Irénée du Pont (1771-1834). In 1903 the DuPont Company's Executive Committee established the Experimental Station, a research facility located on the banks of the Brandywine Creek across from DuPont's first black powder works. This collection contains photographs of general views of the Experimental Station showing its growth over time.

James R. Thomen (1926-) was manager of the Experimental Station from 1975 to 1985 when he retired. The DuPont Company's Experimental initially, was to be a small laboratory to screen inventions which were coming into the company from outside independent inventors specifically for research on black powder, smokeless powder, and dynamite, but soon its mission was altered and it became a large industrial research facility focused on innovative advancements in chemistry. This collection consists primarily of photographs of buildings at the Experimental Station in Wilmington, Delaware taken between 1910 and 1950.