Edward B. du Pont (1934-2017) was vice president of the Wilmington Trust Company, served on numerous boards of directors, and was descended from the founders of E.I. du Pont de Nemours & Company, a chemical company more commonly referred to as the DuPont Company. This small collection documents Edward B. du Pont's service on the boards of directors for the DuPont Company, Atlantic Aviation, and the Hagley Museum and Library, as well as the board of trustees for the University of Delaware, primarily through group portraits. His work for the DuPont Company is most heavily represented. The collection is arranged chronologically. The majority of images date from 1977 to 2003.

Greta Brown Layton (1924-2014) was a descendant of Pierre Samuel du Pont de Nemours (1739-1817) who founded the E.I. du Pont de Nemours & Company with his son Eleuthère Irénée du Pont (1771-1834) in 1802. The E.I. du Pont de Nemours & Company is a chemical company more commonly referred to as the DuPont company. This collection consists of family portraits and group photographs of ancestors of Greta Brown Layton. The bulk of the collection are portrait engravings of individual members of the du Pont, Hounsfield, Pelleport, Van Dyke, Barksdale, and related families.

Lammot du Pont (1831-1884) was a chemist and inventor, he was the grandson of Eleuthere Irenee du Pont (1771-1834), founder of E.I. du Pont de Nemours & Company, more commonly known as the DuPont Company. This collection contains photographs of Brandywine, Hagley area, and the family of Lammot du Pont and Mary Belin du Pont (1839-1913).

Andrew Gray Wilson (1844-1905) was well-known among shipbuilders as a preeminent marine engineer and naval architect. This small collection consists primarily of individual and group portraits and snapshots of the Wilson family and the family of one of the daughters, Natalie Wilson du Pont. The collection is organized into three series; family photographs; home interiors and exteriors; and family cars and dogs photographs.