Francis Victor du Pont (1894-1962) was a civil engineer and political figure in Delaware and Maryland. This collection combines papers and memorabilia of Francis Victor du Pont and those of his parents and ancestors.

Irene "Sophie" Sophie du Pont May (1900-2001) was a churchwoman, a philanthropist, and a descendant of Pierre Samuel du Pont de Nemours (1739-1817) who founded the E.I. du Pont de Nemours & Company with his son Eleuthère Irénée du Pont (1771-1834) in 1802. The E.I. du Pont de Nemours & Company is a chemical company more commonly referred to as the DuPont company. The collection consists of Sophie du Pont May's family correspondence and financial correspondence as well as correspondence between her father Irénée du Pont (1876-1963) and his older sister Louisa d'Andelot du Pont Copeland (1868-1926).