American Car and Foundry Company is a manufacturer of railroad rolling stock and railcar parts, founded in 1899. In 1901, the company began leasing the facilities of a railroad rolling stock and shipbuilding manufacturer, the Jackson and Sharp Company. The records include photocopies of a history of the Wilmington plant, incorporation papers, and deeds.

Bellevue estate, now the Bellevue State Park, is a historic estate that was once a series of farms owned by members of the Orr, Grubb, and Stevenson families and later purchased by William du Pont (1855-1928). The records are a series of deeds covering the conveyance of the Bellevue property from 1782 to 1920. There are also three maps of the estate, including one showing the location of the house and landscaping.

Oliver Canby (1716-1754) was a miller on the Brandywine Creek. This collection of deeds and indentures documents the acquisition of mills or mill seats, and other lands near the Brandywine Creek in Wilmington, Delaware by the Canby family. This collection was in the possession and care of the Canby family until it was given to Hagley Museum and Library in 2011 by a descendant of Oliver Canby.

Abraham Dupont (1572-1640) was the progenitor of the South Carolina branch of the Du Pont family. In France, he dealt in manufactures of brass and copper. This is a small collection of his papers and those of his immediate descendants. The documents include the earliest records still extant in the Du Pont family papers. They are important for the evidence of descent they offer and for details about the ancestors of Pierre Samuel du Pont de Nemours (1739-1817). Many relate to landed property in Rouen and in the nearby parishes of Fontaine-sous-Préaux and Roncherolles.

The Edge Moor Iron Company engaged in the manufacture of iron and steel bridges at a plant located on the Delaware River north of Wilmington. The collection is comprised of a limited selection of documents, primarily connected to the liquidation of the company in 1936. It includes plant and property maps, clippings, and deeds and titles covering the property.

Joshua Gilpin (1765-1841) was a merchant and paper manufacturer. Thomas Gilpin (1776-1853) went into business with his brother, Joshua, establishing Delaware's first paper mill on the Brandywine Creek. James Riddle (1802-1873) owned James Riddle Son & Co., a cotton mill along the Brandywine. This collection contains miscellaneous papers from the three men, including deeds, property agreements, and a copy of Riddle's will.

The Lea family was among the largest flour mill operators at the Brandywine Falls, near Wilmington, Delaware, since the 1770s, when Thomas Lea (1757–1823) joined in partnership with Joseph Tatnall (1740–1813) to operate mills on the north bank of the stream. This small collection of Lea family papers documents Delaware and Pennsylvania land use and ownership, elite family and social relationships, and agricultural business operations from the early eighteenth century to the mid-nineteenth century. The materials are from four generations of the William Lea (1805-1876) family lineage. The collection is arranged into four series: Real estate and financial papers, Correspondence, Personal papers, and Newspaper clippings.

Several generations of the Penn family were proprietors of the British colony of Pennsylvania. It was given to William Penn (1644-1718) in 1681 by Charles II of England in repayment of a debt owed to his father, Sir Admiral William Penn (1621-1670). Under Penn's directive, Pennsylvania was settled by Quakers escaping religious torment in England and other European nations. Three generations of Penn descendants held proprietorship of the colony until the American Revolution, when the family was stripped of all but its privately held shares of land. "Book A" is a record of deeds granted between April 24, 1784, and March 22, 1793, by members of the Penn family to various purchasers of those proprietary lands retained by the family after the American Revolution, located between Philadelphia and Pittsburgh.

The Reading Company, chartered in 1871 as the Excelsior Enterprise Company, became the holding company for the system of railroads, canals and coal mines assembled by the predecessor Philadelphia & Reading Railroad Company between 1833 and 1896. The Reading Company employment and real estate records comprise a largely incomplete and extremely fragmentary synthetic collection of material related to the Philadelphia & Reading Railroad Company and its successors. The collection comprises incomplete employment records largely dating from the first half of the twentieth century, records related to the employee pension program and the Relief Association, a small amount of contracts, and deeds and agreements reflecting the company's process of land acquisition following initial main line construction in the 1830s and through to the early twentieth century.

The Savery family of Chester County, Pennsylvania, produced two generations of eminent mechanical engineers. Savery family papers consists of materials of the eldest son William H. Savery's (1865-1949) diaries, his father Thomas H. Savery (1837-1910) correspondence and notebooks documenting his career as a mechanical engineer, and the documents relating to Savery/Webb family property near Longwood Gardens, Hamorton and Parkerville, Pennsylvania.

The Morris family of Philadelphia were brewers, merchants, land speculators, manufacturers, and prominent participants in public affairs. Their papers are primarily from Samuel and Isaac W. Morris. However, the collection includes papers from other family members from the first Anthony Morris to John Thompson Morris (1847-1915), the founder of the Morris Arboretum in Germantown. There are also papers from members of the Wistar, Paschall, and Mifflin families allied by marriage.

William Henvis (1809-1858) was an employee of E.I. du Pont de Nemours & Company. The records are two property deeds of William and Margaret Henvis, one for purchase of land in 1849 and one for sale of land in 1850.