Pierre Samuel du Pont de Nemours (1739-1817) was a French political economist, writer, publisher, and public administrator. He was an advocate for a national educational system and promoted Franco-American trade relations. Françoise (Robin) Poivre (1748-1841) was the second wife of Pierre Samuel. Françoise Julienne Ile de France (Poivre) Bureaux de Pusy (1770-1845) was a daughter from Poivre's first marriage. This collection includes a small selection of correspondence, including details on the family's immigration to the United States from France and Bureaux de Pusy's financial problems.

Henry du Pont (1812-1889) was an American military officer and son of Eleuthère Irénée du Pont (1771-1834), founder of E.I. du Pont de Nemours & Co., and Sophie Madeleine Dalmas du Pont (1775-1828). The collection consists of photocopied letters from Henry du Pont (1812-1889) and typescript of Pierre Samuel du Pont de Nemours (1739-1817) autobiography he wrote in 1792. The letters are from sisters Eleuthera du Pont Smith (1806-1876) and Sophie Madeleine du Pont (1810-1888), as well as William Tecumseh Sherman (1820-1891) and M. Saito of the Japanese Navy.