Pierre Samuel du Pont de Nemours was a French political economist, writer, publisher, and public administrator. He was an advocate for a national educational system and promoted Franco-American trade relations. Francoise (Robin) Poivre du Pont was his second wife. His grandson, Samuel Francis du Pont (1803-1865) was a Rear Admiral in the United States Navy and fought in the Mexican-American War and the Civil War. This collection consists of twenty-three photocopied letters, primarily from Pierre Samuel du Pont de Nemours (1739-1817), but also Francoise du Pont de Nemours (1748-1831) and Samuel Francis du Pont (1803-1865). The correspondence is primarily to Marie Anne Lavoisier Thompson (1758-1836), a French chemist and close friend of the family.