Crawford H. Greenewalt (1902-1993) was an executive with the DuPont Company and president of the firm from 1948 to 1962. In 1942, when the DuPont Company agreed to participate in the Manhattan Project, Greenewalt was named chief liaison, working with the physicists at the University of Chicago Metallurgical Laboratory, including Arthur Compton (1892-1962) and Enrico Fermi (1901-1954), who were developing techniques for plutonium separation. The collection consists of eight volumes of Greenewalt's diaries, which describe the history of the Manhattan Project and the development of the United States' first atomic bombs that were used to end the Second World War. The diaries describe the technical history of the project, as well as the relationships that developed between scientists.

E.I. du Pont de Nemours & Company is a chemical company more commonly referred to as the DuPont company. The company was established in 1802 for the production of black powder. This collection includes publicity photographs from the DuPont Company, many relating to nylon and its uses in World War II. Other subjects include company executives, employees, and stock holders; various factories and facilities; general World War II production awards; high explosives workers; and hunting.

E.I. du Pont de Nemours & Company is a chemical company more commonly referred to as the DuPont Company. The DuPont Building occupied an entire block bound by 10th, 11th, Orange and Market Streets and was one of the first high-rises in Wilmington, Delaware. Until early 2015 the building housed DuPont's headquarters. This small collection of files on DuPont Company history and biographies were removed from the company's downtown headquarters building prior to its move to the suburbs.

During World War II, the DuPont Company was contracted to produce smokeless powder, TNT and DNT explosives for the military. This panoramic photograph is a group portrait of uniformed guards at a military explosives plant in Memphis, Tennessee, 1941.