E. Paul du Pont (1887-1950) established Du Pont Motors, Inc., a manufacturing company of luxury automobiles, in 1919 in Wilmington, Delaware. He worked for a short time at the family business, E.I. du Pont de Nemours & Company which manufactured gunpowder. He was one of ten children of Francis Gurney du Pont (1850-1904) and Eliza Wigfa Simons du Pont (1849-1919). This small collection contains photographs of DuPont powder yards; family photographs; home exteriors; and postcard views of Longwood Gardens.

Éleuthère Irénée du Pont de Nemours (1771–1834) was a French American chemist and industrialist who founded the gunpowder manufacturer E.I. du Pont de Nemours & Company. E.I. du Pont married Sophie Dalmas du Pont (1775-1828) in 1791; the couple had eight children, one of whom died in infancy. This collection of papers includes outbound and inbound correspondence covering personal and business matters. These include personal accounts, writings and memoirs, legal documents, and miscellany, of which the majority are accounts. There are papers of the E.I. du Pont de Nemours & Co. that date from 1802 to 1850 and include correspondence (drafts, retained copies, and letters received), contracts and other legal documents, accounts, bills and receipts, checks, promissory notes, bills of exchange, drafts, and certain miscellaneous notes and memoranda.

Éleuthère Irénée du Pont de Nemours (1771–1834) was a French American chemist and industrialist who founded the gunpowder manufacturer, E.I. du Pont de Nemours and Company. E.I. du Pont married Sophie Dalmas du Pont (1775-1828) in 1791, and the couple had eight children, one of whom died in infancy. This collection primarily consists of E.I. du Pont's personal and business correspondence; writings and notes; school materials; memoranda on manufactures and tariffs; legal agreements; patents; and land surveys. Also included are Sophie Dalmas du Pont's correspondence and household account records.

Francis Gurney du Pont (1850-1904) was the youngest son of Alexis I. du Pont (1816-1857) and Joanna Smith du Pont (1815-1876), and grandson of Éleuthère Irénée "E.I." du Pont (1771-1834), founder of E.I. du Pont de Nemours & Company, a chemical company more commonly referred to as the DuPont Company. The collection contains two letter books of du Pont to F.G. Thomas (-1901) of the Iowa Powder Mills, photocopies of selected documents by Benjamin Franklin (1706-1790) on gunpowder, and on awards to John Paul Jones (1747-1792) for his victory over HMS Serapis, and letter from Samuel Courtauld (1752-1821) to Captain Joseph H. Rees (1789-1821).

Francis Gurney du Pont (1850-1904) was the youngest son of Alexis I. du Pont (1816-1857) and Joanna Smith du Pont (1815-1876), and grandson of Éleuthère Irénée "E.I." du Pont (1771-1834), founder of E.I. du Pont de Nemours & Company, a chemical company more commonly referred to as the DuPont Company. The papers of du Pont describe both his business activities at E.I. du Pont de Nemours & Company, his family life, and his activities in the Episcopal Church.