Bill Mackey (1906-1996) was a chemical engineer and the plant manager of the Technical Division of the Explosives Department of the E.I. du Pont de Nemours & Company (DuPont Company).

Bill Harry Mackey was born on May 8, 1906, in Denver, Colorado, and received his Ph.D. in industrial chemistry from the University of Illinois in 1929. He joined the DuPont Company as a chemical engineer at the Belle, West Virginia, plant in 1930, and from 1932 to 1941, he worked as a research chemist at the Explosives Department's Burnside Laboratory in Carney's Point, New Jersey.

During World War II, Mackey worked at three defense plants that the DuPont Company built and operated for the government. He was assistant technical superintendent of the Indiana Ordnance Works from 1941 to 1942, then technical superintendent and eventually assistant plant manager of the Alabama Ordnance Works from 1942 to 1943, and plant manager of the Chickasaw Ordnance Works from 1943 to 1944. In 1944, Mackey was transferred to the Hanford Engineer Works in Richland, Washington, as a technical specialist and was later promoted to plant manager.

Mackey moved to Wilmington, Delaware as manager of the Technical Division of the Explosives Department in 1946. He became manager of the Atomic Energy Division upon its organization in 1950 and was promoted to assistant general manager of the Explosives Department in 1958 and general manager in 1961. Mackey retired on December 31, 1969, and died on March 15, 1996.