Eleuthera du Pont (1806-1876), a daughter of Eleuthère Irénée du Pont (1771-1834) and Sophie Madeleine Dalmas du Pont (1775-1828), was born at the family home, Eleutherian Mills. Her father was the founder of E. I du Pont de Nemours & Company. She was educated at home by her sister, Victorine du Pont Bauduy (1792-1861), and then attended Mrs. Hughes's Boarding and Day School in Philadelphia from 1821 to 1823. She married Thomas MacKie Smith (1809-1852), a physician, in 1834; they had no children. The Smiths toured Europe in 1846-1847. Eleuthera retrieved many of the papers of her grandfather, the physiocrat Pierre Samuel du Pont de Nemours (1739-1817), and brought them back to the United States. After her husband's death, she became more involved with the Brandywine Manufacturer's Sunday School, which served the children of du Pont company workers, succeeding her older sister Victorine as superintendent in 1861. Eleuthera and her younger sister Sophie Madeleine were also interested in family history and genealogy and together arranged and transcribed family papers.