Dr. Alexis Irénée du Pont (1843-1904) was a businessman and non-practicing physician who resided in both Louisville, Kentucky, and Wilmington, Delaware. The Alexis Irénée du Pont family papers primarily consist of both outgoing and incoming correspondence from A. I. du Pont and his immediate family.

Amelia Elizabeth du Pont (1796-1869) was a granddaughter of Pierre Samuel du Pont de Nemours (1739-1817) founder the E.I. du Pont de Nemours & Company, a chemical research, and manufacturing company. She was the eldest child of Victor Marie du Pont (1767-1827) and Gabrielle Josephine de la Fite de Pelleport (1770-1837). The collection contains a photocopy of the act of the Senate and House of Representatives of the State of Delaware by which Amelia Elizabeth du Pont's (1796-1869) marriage to Nathaniel Perkins, alias Nathaniel H. Clifford, was dissolved and a declaration that their child Gabrielle du Pont (1813-1891) was legitimate.

The Dimmick family were descendants of the founders of E.I. du Pont de Nemours & Company, a chemical research and manufacturing company. The collection contains a microfilm copy of correspondence between Joanna (Smith) du Pont (1815-1876) and her daughter, Joanna (du Pont) Dimmick (1854-1901), and letters from Sophie M. du Pont (1810-1888) to her niece, Dimmick, and the latter's step-daughter, Lavinia Elizabeth Dimmick (1874-1946). The letters are personal in nature, including du Pont family news.

This collection of family correspondence encompasses several generations of the du Pont, Kemble, and de Forest families. Victorine du Pont (1825-1887), the eldest child of Alfred Victor du Pont (1798-1856), senior partner in E.I. du Pont de Nemours & Company, and Margaretta Elizabeth (Lammot) du Pont (1807-1898), married Peter Kemble (1825-1887), son of William Kemble the company's New York business agent. One of their daughters, Meta Kemble (1852-1933), married New York artist Lockwood de Forest (1850-1932).

Eleuthère Irénée du Pont (1771-1834), founder of E.I. du Pont de Nemours & Co., and Sophie Madeleine Dalmas du Pont (1775-1828) had four daughters. This group of materials within the Winterthur Manuscripts collection contains the papers of the three eldest: Victorine (du Pont) Bauduy (1792-1861), Evelina (du Pont) Bidermann (1796-1863), and Eleuthera (du Pont) Smith (1806-1876), as well as their respective husbands: Ferdinand Bauduy (1791-1814), James Antoine Bidermann (1790-1865), and Thomas MacKie Smith (1809-1852). Victorine du Pont Bauduy and Eleuthera du Pont Smith were teachers at the Brandywine Manufacturers' Sunday School (BMSS), a nonsectarian school offering classes in reading, writing, arithmetic, and Bible lessons. Evelina du Pont Bidermann spent much of her adult life traveling alongside her husband and then building the Winterthur mansion in Delaware. Their papers document details about their education, social life, family, attitudes, and activities through incoming and outgoing correspondence, as well as personal papers such as diaries and account books.

Eleuthera du Pont Smith (1806-1876) and Sophie Madeleine du Pont (1810-1888) were daughters of Eleuthère Irénée du Pont (1771-1834) and Sophie Madeleine Dalmas du Pont (1775-1828). This collection contains letters from the du Ponts to Mary Wilkinson, a former student at the Brandywine Manufacturers' Sunday School. The letters discuss domestic matters, including family news, health, faith, and needlework for the mills.

Elise Simons du Pont (1849-1919) was the wife of Francis Gurney du Pont (1850-1904), a vice president of E.I. du Pont de Nemours & Co., a chemical company more commonly referred to as the DuPont Company. The records consist of itemized household receipts, primarily from three Wilmington, Delaware grocers and one from John Wanamaker's department store in Philadelphia. The receipts give descriptions of goods and prices.

Eugene du Pont Jr. (1873-1954) was a director of the E.I. du Pont de Nemours & Company from 1917 until 1954, and a great grandson of company founder, Éleuthère Irénée du Pont (1771-1834). The collection contains the personal papers of Eugene du Pont, Jr., and the records of the Kinloch Gun Club, a private shooting club which he founded. It also contains a separate collection of correspondence between his brother Alfred I. du Pont, vice president and general manager of the DuPont Company, with his assistant Frank L. Connable, which is an important source for the history of the company in the early 1900s.

Eugene du Pont (1840-1902) was the eldest son of Alexis I. du Pont (1816-1857) and Joanna Smith du Pont (1815-1876) and joined the E.I. du Pont de Nemours & Co., eventually rising to president in 1899. The bulk of the papers in this small collection are letters sent to Eugene du Pont by his mother while he was in school in Philadelphia from 1857 to 1859.

Gabrielle Josephine de La Fite de Pelleport (1770-1837) was the wife of Victor du Pont (1767-1827), a French American diplomat, politician, and businessman. He was the brother of Éleuthère Irénée du Pont (1771-1834), the founder of the E.I. du Pont de Nemours & Company. The account book is supposedly the household account book of du Pont and contains handwriting of various people, including her son Charles I. du Pont (1797-1869). Entries include purchases of coal, whiskey, soap, candles, and other items, as well as construction materials and tools.

Henry Belin du Pont (1898-1970) was a research engineer with General Motors and the vice president of E.I. du Pont de Nemours & Company from 1939 to 1963. This collection contains correspondence from several generations of the family from the early nineteenth through the twentieth century, including Francis Gurney Smith (1784-1873), Elizabeth (Eliza) MacKie Smith (1787-1861), Joanna Smith du Pont (1815-1876), Frances du Pont Coleman (1838-1902), Eleuthera "Ella" du Pont Bradford (1848-1906), Eleuthera Bradford du Pont (1873-1953), Alicia Bradford Maddox (1875-1920) and Phoebe George Bradford (1794-1840).

Lavinia Dimmick Rée (1874-1946) was a descendant of the founders of E.I. du Pont de Nemours & Company, a chemical research and manufacturing company. She was the daughter of Irene du Pont (1845-1877) and Edward Dimmick (1843-1895), and a great-niece of Sophie M. du Pont (1810-1888). The records consist of two copies of a typewritten transcription of "Memories of Aunt Sophie" written by Rée about du Pont's home, Lower Louviers, during the late 1870s and 1880s.

Margaretta “Meta” du Pont Coleman (1862-1938) was a descendant of Pierre Samuel du Pont de Nemours (1739-1817) who founded the E.I. du Pont de Nemours & Company with his son Eleuthère Irénée du Pont (1771-1834) in 1802. The E.I. du Pont de Nemours & Company is a chemical company more commonly referred to as the DuPont company. The Margaretta E. "Meta" du Pont Coleman Papers primarily consist of family correspondence collected by Meta Coleman.

Mary Belin (1839-1913) married Lammot du Pont (1831-1884) and had eleven children, many who were prominent in the building up of the E.I. du Pont de Nemours & Company. The volume consists of a typed transcript of letters originally sent to Mary Belin du Pont (1839-1913) by her daughters Louisa ("La") (1868-1926), Sophie M. ("Tabby") (1871-1894), Isabella ("Bella") (1882-1946), and Margaretta ("Peg") (1884-1973) in 1894. The letters center around a single incident wherein Sophie, who was suffering from tuberculosis, was sent to Colorado Springs for a cure.

Mary Belin (1839-1913) married Lammot du Pont (1831-1884) and had eleven children, many who were prominent in the building up of the E.I. du Pont de Nemours & Company. The collection includes a carbon copy of a typed transcript from Belin's recipe book. The recipe book included dishes typical of middle class Americans in the Northeast in the early and mid-nineteenth century, as well as home remedies, household hints, and how to prepare paints and dyes.

Sophie Madeleine du Pont (1810-1888) was the youngest daughter of Eleuthère Irénée du Pont (1771-1834), founder of E.I. du Pont de Nemours & Co., and Sophie Madeleine Dalmas du Pont (1775-1828), and the wife of Samuel Francis du Pont (1803-1865). In the letter to Mary Ann (Hogg) Brunot (1822-1899), du Pont thanks her for a sermon Brunot sent and reflects du Pont's concern with religious and domestic matters.

Victor Marie du Pont (1767-1827) was a French diplomat. In 1794, he married Gabrielle Joséphine de La Fite de Pelleport (1770-1837), and a year later they came to the United States, where he was appointed as consul at Charleston, South Carolina. They returned to France in 1798, but came back to the United States in 1800 with their children; his father, Pierre Samuel du Pont de Nemours (1739-1817); and his younger brother, Éleuthère Irénée du Pont (1771-1834), and his family. Victor and Joséphine du Pont had five children, four surviving to adulthood: Amelia Elizabeth (1796-1869), Charles Irénée (1797-1869), Samuel Francis (1803-1865), and Julia Sophie (1806-1882). (The papers of Samuel Francis Du Pont, husband of Sophie Madeleine Du Pont, are held in Group IX of the Winterthur Manuscripts.) The collection is arranged into three series: Amelia du Pont papers, Charles Irénée du Pont and his wives' papers, and Julia (du Pont) Shubrick and her husband, Irvine Shubrick papers. The papers consist primarily of personal correspondence with family and friends.

Victorine du Pont (1792-1861) was the eldest child of Eleuthère Irénée du Pont (1771-1834), founder of E.I. du Pont de Nemours & Company, and Sophie Dalmas du Pont (1775-1828). Ferdinand Bauduy (1791-1814) was the son of Peter Bauduy (1769?-1833), business partners with du Pont in DuPont, Bauduy, & Co., and Theresa Bretton des Chapelles (1773-1837). This collection is a copy of their marriage certificate in 1813.

Victorine du Pont (1792-1861), the eldest child of Eleuthère Irénée du Pont (1771-1834), founder of E.I. du Pont de Nemours & Company, and Sophie Dalmas du Pont (1775-1828). The album contains poetry and verses written by Victorine and her friends and family, sketches, and watercolors.

Walt Biddle (1925-1995) was a gardener in the household of Louise du Pont Crowninshield (1877-1958) and Francis B. Crowninshield (1869-1950) at Eleutherian Mills in Greenville, Delaware. In his oral history interview transcript, Biddle describes the Crowninshields and life at Eleutherian Mills in the 1940s and 1950s.

Wilhelmina du Pont (1906-2000) was the daughter of William K. du Pont (1875-1907) and Ethel Hallock (1876-1951), a fourth generation descendent from E.I. du Pont (1771-1834). The letters are to Wilhelmina du Pont from her cousin Alice (Belin) (Mrs. Pierre S. du Pont) (1872-1944); mother Ethel (Mrs. William Kemble du Pont); cousin Alice (du Pont) (Mrs. T. Coleman du Pont) (1863-1937); and uncle Pierre S. du Pont (1870-1954).