E.I. du Pont de Nemours & Company was established in 1802 by Pierre Samuel du Pont de Nemours (1739-1817) and his son Éleuthère Irénée du Pont (1771-1834). This collection of more than 1250 discrete photographs depicts the landscape and buildings at or near the company's explosives manufacturing plants along Brandywine Creek near Wilmington, Delaware. Approximately 900 images depict powder yard sites, including the DuPont Experimental Station, either during the mills' final decades of operation or prior to, during, and after excavation and restoration work on the site in the 1950s and 1960s. Most of the remaining images depict the worker communities which surrounded the powder yards.

DuPont, Washington, was built by E.I. du Pont de Nemours & Company for the purpose of housing employees of its dynamite plant. The collection includes papers on the history of DuPont, specifically the nomination to the National Register, along with copies of newspaper clippings, maps, and reports related to the nomination.

The War Department of the United States Government contracted with the DuPont Company to build and run a smokeless powder plant called the Old Hickory plant on the Cumberland River near Nashville, Tennessee during World War I. These panoramic photographs show overall views of DuPont Company's Old Hickory smokeless powder plant, also views of exterior and interior details.

In 1902, DuPont took control of Laflin & Rand, including the Haskell Works. Infallible and Ballistite powders were manufactured there. The works played an important role in smokeless powder production during World War I. The panoramic photographs depict views of the Du Pont Company's smokeless powder works in Haskell, New Jersey and the workers village nearby.

Wawaset Park was a planned residential community built by the DuPont Company around 1918 for its executives in Wilmington, Delaware. These panoramic photographs depict construction of homes and overall views of area, street scenes, and pictures of individual houses.